Senior Scientist, Cell Culture

Key

responsibilities :

Perform hands-on laboratory work in the cell line and

upstream process development team contributing to the development

of processes suitable for technology transfer to the cGMP

manufacturing teams. An understanding of cGMP manufacturing

facility constraints and their impact on development activities

will be developed.

Contribute to process

validation / characterization activities by performing supporting

laboratory scale studies, employing DOE methodologies.

Interpret analytical data provided by the analytical team

to define subsequent steps.

Deliver high

quality communication to ensure an outstanding customer experience

(written reports, telecons, face to face meetings)

Working as part of a site and global project team,

co-ordinate multiple projects and ensure timely delivery of project

work stages. Supervision of small project teams may also be

required.

Cell Culture process include : Cell

Line Development (routine cell culture, FACS); Process Development

(ambr15 miniaturized bioreactors, 10L laboratory scale

bioreactors); Process Characterization (ambr250 miniaturized

bioreactors, 10L laboratory scale

bioreactors)

Key

Requirements

Degree / PhD or equivalent experience in a field of Science

that is relevant.

Proven experience required,

including a PhD or equivalent experience gained in a lab in either

industry or academia, or through an industry work training

program.

Detailed understanding of the theory

and application of recombinant protein expression using mammalian

cell culture systems.

Understanding of cGMP

regulations.

Excellent problem solving,

analytical and team working skills.