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Research Fellow : Enzyme engineering / synthetic biology (CNegSAF Project) - CNRS@CREATE LTD.

Research Fellow : Enzyme engineering / synthetic biology (CNegSAF Project) - CNRS@CREATE LTD.

CNRS@CREATE LTD.D05 Clementi New Town, Hong Leong Garden, Pasir Panjang, SG
15 days ago
Job description

Roles & Responsibilities

A two-year Post-doctoral position in enzyme engineering / synthetic biology is available at CNRS@CREATE, Singapore

Overview

A Post-Doctoral position in enzyme engineering / synthetic biology is available at the Campus for Research Excellence and Technological Enterprise (CREATE) in Singapore . Hosted by CNRS@CREATE, the program ‘Carbon Negative production of advanced Sustainable Aviation Fuels using twin synthetic bacterial consortia Project’ (CNegSAF) is an international collaboration between world leading institutions in France and Singapore including CNRS, Toulouse Biotechnology Institute (TBI), National University of Singapore, A

  • Star (SIFBI), and Nanyang Technological University . CNegSAF aims to demonstrate the feasibility of using a synthetic bacterial consortium to convert green hydrogen and concentrated waste CO2 (released by chemicals companies) into sustainable aviation biofuels. This innovative research program has the potential to significantly contribute to Singapore's and the world net-zero emissions target while supplying sustainable aviation fuels to the aviation industry.

Job description

To join this team, we are looking for a candidate who will be in charge of enzyme engineering activities using state-of-the-art evolutionary engineering and will also be involved in the development of screening protocols, construction and screening of enzyme libraries, designed by in silico molecular modelling methods. These enzymes will be further integrated into metabolic pathways for the in vivo production of diverse terpenoids.

The prospective researcher will work in a multidisciplinary environment with access to High-Throughput Screening equipment (both in Singapore and Toulouse, France) and have frequent and strong interactions with other scientists involved in metabolic engineering, pathway engineering and computational enzyme design.

Required education & skills

  • PhD in Molecular Biology, Biochemistry, Biochemical Engineering or related field.
  • Experience with enzyme engineering and enzyme library construction
  • Expertise with HT screening, assay design, development and troubleshooting
  • Experience in bioinformatics, structural biology and molecular modelling would be a plus
  • Preferred experience with protein production, purification, characterization and crystallization knowledge
  • Preferred experience with metabolic engineering / synthetic biology background
  • Strong communication and organizational skills, and enjoy working in a team-oriented environment.
  • Good English skills are required.
  • Salary & Appointment terms

    Salary range : SGD 6,900 – SGD 10,000 (depending on suitability and experience)

    The positions are available starting in November 2025 and for a duration of up to two years (possibility of extension). The position will be mainly based in Singapore with possible visiting stays in Toulouse, France.

    Further information & Contacts

    Applicants should send as soon as possible CV, summary of previous research and contact addresses of two references to :

    Isabelle ANDRÉ (TBI, Toulouse, France) : isabelle.andre@insa-toulouse.fr

    Xixian CHEN (A

  • SIFBI, Singapore) : xixian_chen@sifbi.a-star.edu.sg
  • Bo XUE (SynCTI-NUS, Singapore) : xuebo@nus.edu.sg

    Thomas LAUTIER (TBI, Toulouse, France) : thomas.lautier@insa-toulouse.fr

    Ee Lui ANG (A

  • SIFBI, Singapore) : ang_ee_lui@sifbi.a-star.edu.sg
  • Tell employers what skills you have

    Biochemistry

    Aviation

    Construction

    Enzymes

    Biofuels

    Aviation Industry

    Molecular modelling

    Purification

    Biotechnology

    Biology

    Enzyme Assays

    Characterization

    Teamoriented

    Synthetic Biology

    Molecular Biology

    Screening

    Molecular Modeling

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    Research Fellow • D05 Clementi New Town, Hong Leong Garden, Pasir Panjang, SG

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